Monthly Archives: September 2019

Single cell studies, new technique established at K2

The Human Cell Atlas Project is an international collaborative effort that aims to define all human cell types in terms of distinctive molecular profiles (such as gene expression profiles) and to connect this information with classical cellular descriptions (such as location and morphology). This quote is from the presentation of “The Human Cell Atlas” in eLife. The Human Cell Atlas Consortium is an international collaborative project aimed at describing all types of human cells and linking this information with classical cell biology knowledge such as localization and morphology. The atlas will be openly available to all researchers. In June, The Chan Zuckerberg Initiative granted $ 68 million to 38 research groups around the world to study various organs and systems (like the immune system) in different populations using blood and organ specimens (organ donors, surgical tissue). In the next few years a host of information will be available to increase our understanding of normal physiology and pathology.

Some of the research groups at K2 have started using these methods, but now nine different groups at our faculty have pitched in money to buy the10X Genomics technology, making it easier to get started with single-cell studies. With 10x technology, up to 10,000 single cells can be studied in one experiment. The technique is based on the isolation of single cells in oil droplets together with a package of barcoded primers. In addition to RNA-seq 10x performs copy number profiling, ATAC sequencing at single cell resolution and long read genome- and exome sequencing (https://www.10xgenomics.com/). This enables one to extract information about the individual cell after bulk sequencing of the sample, and for example construct a tissue map where the cells are grouped according to properties. The technique opens up a wealth of opportunities to study disease processes at the single cell level and test out various treatments. A nearby example is cancer treatment and treatment responses to various tumor cells.

The 10X machine will be located on the Flow Cytometry Core Facility at K2. Those interested can contact the Core Facility for further information. I hope that many groups will seize the opportunity to use single cell techniques.

Good luck

Eystein Husebye

Seminarserie Senter for ernæring, onsdag 2. oktober

Senter for ernæring har gleden av å invitere til et nytt seminar i vår seminarrekke. Serien tar opp sentrale utfordringer innen ernæring og helse.

Tid: Onsdag 2. oktober kl. 14.30-15.30

Sted: Auditorium 2, BB-bygget, Jonas Lies vei 91

Computational Data Analytics on the Web for Better Food Decision

Speaker: Christoph Trattner 

Moderator: Gülen Arslan Lied

Christoph Trattner is an Associate Professor at the University of Bergen at the Information Science & Media Studies Department. Previously, he was an Asst. Prof. at MODUL University Vienna at the New Media Technology Department. He also founded and led the Social Computing department at the Know-Center, Austria’s research competence for data-driven business and big data analytics.

According to the World Health Organization around 80% of cases of heart disease, strokes and type 2 diabetes could be avoided if people were to implement a healthier diet. Computational data analytics approaches have been touted as a valuable asset in achieving the ambitious goal of understanding user behavior and being able to develop intelligent online systems, which can positively influence people’s food choices. In this talk, he will present his latest research on computational data analytics approaches to understand, predict and potentially change food decision making in an online context.

Det blir lett servering.

Velkommen!

http://www.uib.no/ernaring

Immunology, stem cell treatment and cancer medicine

The Biomedical Network invites you to a seminar on Immunology, stem cell treatment and cancer medicine

Time: 16 October at 13.30

Venue: Bikuben, Haukeland University Hospital

Registration here.

The Biomedical Network is a collaboration initiative between Helse Bergen, UiB, Legemiddelindustriforeningen and VIS. The intention behind the network, which is supported by the Research Council of Norway, is to create a joint platform for innovation and project development across academic, public and private actors.

Program
13:30 – 14:35 Åpning

Forskningsdirektør/Førsteamanuensis Eli Renate Grüner, Helse Bergen/UiB 

Autolog stamcellebehandling

Overlege/Professor Lars Bø, Helse Bergen/UiB

Immunologiske preparater

Arnt-Ove Hovden, Medical Affairs Lead & Medical Manager hos Boehringer Ingelheim

Immunterapi ved melanom

Overlege/Professor Oddbjørn Straume, Helse Bergen/UiB

Hvilke muligheter opplever farmasøytiske firma innenfor immunologisk terapi

Andrey Solokov, Medical Advisor hos AbbVie

14:35 – 15:05 Mingling og lett servering
15:05 – 15:50 Støtteordninger fra forskningsrådet

Spesialrådgiver Rigmor Fardal, Forskningsrådet

NorCRINs arbeide for å bedre forholdene for kliniske utprøvingsstudier

Overlege Camilla Tøndel, NorCRIN/Helse Bergen

Pasienterfaringer fra deltakelse i kliniske utprøvingsstudier

15:50 – 16:05 Pause
16:05 – 16:35 Precision Imaging in Gynecologic Cancer 

Overlege/Professor Ingfrid S. Haldorsen, UiB/Helse Bergen

Advanced medical visualization

Førsteamanuensis Noeska Smit, UiB

Mingling

New name: Cathrine Ebbing

Cathrine Ebbing started working 1.9 2019 in a 50% position as associate professor at K2. I am a specialist in obstetrics and gynecology and have been working at the Women’s Clinic in Bergen since 1999. My specialty is fetal medicine and ultrasound. My research area is both clinical research in fetal and perinatal medicine, but also epidemiological research with data from the Medical Birth Register of Norway. I have been assigned the task of leading the research group “Pregnancy, fetal development and childbirth” under K2 in my position as 50% amanuensis. I am looking forward to that, and to teaching medicine students. She can be contacted on email: Cathrine.Ebbing@helse-bergen.no  Cathrine.Ebbing@molmed.uib.no

 

 

 

New name: Jan Anker

Jan Anker Jahnsen started working in a 20% position as associate professor in July 2019, with academic responsibility for FARM395, a course in pharmacotherapy for fifth year pharmacy students. The main employer is RELIS Vest, the medicines information and pharmacovigilance centre servicing the counties Hordaland, Rogaland and Sogn og Fjordane, which is situated on the 9th floor in the Laboratory-building (Laboratoriebygget). He is cand. pharm from The University of Copenhagen, has a PhD in pharmacology from UiB and will be affiliated with The Bergen Pharmacology & Pharmacy Research Group (G4).

You can get in touch with Jan Anker through e-mail: jan.anker.jahnsen@helse-bergen.no

 

New name: Elham Baghesta

Elham Baghesta started in a permanent 50% position as associate professor 01.09.19 at K2. She have worked at the women’s clinic since 2001 and still work 50% as a general consultant at KK. Her work and research is in obstetrics and on a daily basis she is working mostly with patients with pelvic floor injuries as a result of childbirth.

Email address: elham.baghestan@uib.no

 

New name: Maria Omsland

Maria Omsland Enrolled in a CCBIO Post Doc position at the research group headed by Prof. Bjørn Tore Gjertsen (The signaling-targeted therapy group). Omsland has a BSc in biomedical laboratory sciences and MSc and PhD in Medical Cell Biology which was completed in the same research group in 2017. She just returned from a 2-year long research stay as a visiting fellow at the National Institutes of Health (NIH) and enrolled in the new position at K2 20.08.2019. In her new Post Doc project, she will focus on cell-to-cell communication and signaling in the bone marrow compartment of chronic myeloid leukemia before and during treatment with tyrosine kinase inhibitors. The main methods will be the new imaging mass cytometer (IMC) and 2-photon microscopy of living organisms. E-mail: maria.omsland@uib.no

 

 

 

New publications

Here are recent publications with contributions from K2 based on last week’s search on PubMed (and optionally articles that have not been included in previous lists). This time the list includes in total 7 recent publications. The entries appear in the order they were received from NCBI. If you have publications that are not included in this or previous lists, please send the references to Hege F. Berg.

Continue reading

Time for registration of side line jobs

I write this editorial onboard my flight to Vienna. There we have Allgemeine Krankenhaus, the hospital where Ignaz Semmelweis demonstrated the connection between doctors and midwives’ lack of hand hygiene and the prevalence of puerperal fever. Our class at medical school visited the hospital and were able to follow an excellent round from an undoubtedly important professor with a looooong tail of people behind….. Good memories! Maybe I will have time to stop by again, although my mission is now to focus on genetics and not the environment by giving a lecture on monogenic diabetes at the annual meeting of the European Study Group for Pediatric Endocrinology.

These types of congresses provide important academic replenishment. The funding of travel and accommodation changed drastically many years ago to maintain clearer lines between university and health care professionals and for-profit businesses, which I think was right in terms of potential competition as well as individual loyalty. That brings me to side line jobs, and our duty to update them twice a year.

By side line jobs is meant job placement, job acquisition, assignments and assignments that an employee at UiB has outside his / her position at UiB, regardless of whether the work or job is paid or not. Work carried out for an enterprise or company wholly or partly owned by the employee is also regarded as a side line job.

The principles for side line jobs can be found in UiB’s Regelsamling (Norwegian only) and apply to all UiB employees, irrespective of the category of job and the number of positions. They must protect our reputation and the trust and integrity of the employees. There should be openness about side line jobs that may have an impact on the work of the university. Everyone must report on their own side assignment on their own initiative.

The following need not be registered: Membership in external review committees, referee for professional journals, assignments as external examiner, professional assignments that accompany main position or individual minor assignments in teaching or dissemination at other institutions, or unpaid appointments of limited scope for non-profit institutions.

The following must be reported: Side line jobs that may be in competition with the University’s activities, are of a long or extensive nature, and may cast doubt on the employee’s loyalty, willingness or ability to carry out his work at the University in the manner indicated by the position and the University’s purpose, and persistently use of the university’s resources and infrastructure.

Applications for side line jobs are evaluated according to the University’s principles for side line jobs, see above. Both registration of page tasks that require approval, and those that are only to be registered, are done in Pagaweb. Information about the side line jobs is stored there and will be made publicly available.

The Department Head approves or rejects applications. Rejection of an application can be appealed to the Faculty Board or the University Director. Violation of the principles of side-tasks can lead to personnel consequences under the Civil Service Act and other reactions under the rules of default in the civil service.

This may seem negative? No, side assignments are positive as long as it does not hamper or slow down our regular work, can damage the university’s reputation, or mix its own and the university’s resources.

Have a great weekend!

Progress report NFR – deadline October 1st or 31st

If you have an ongoing project at NFR, you may have been notified to submit Progress report via “My RCN web”. The report layout concerns academic progress.  We would also recommend that you request a report from your financial controller about unused funds for 2019. Last year, the NFR came last week in November, reminding us that unused project funds for the calendar year must be applied transferred to the following year. If you have large residual funds for 2019 (can be clarified with the financial controller), we recommend that you submit an application for a project change as soon as possible.

 

(Norwegian) Kjenner du studenter som kan søke Aker Scholarship?

UiBs studenter har mange muligheter foran seg, blant annet fins det noen særlig ettertraktede stipendordninger for masterstudenter og ph.d.-kandidater.

Jeg var nylig i møte med Aker Scholarship som nettopp er en slik gunstig stipendordning og døråpner til noen av verdens beste universiteter. Gjennom deres stipender slipper norske studenter å pådra seg studielån ved utenlandsopphold, og samtidig kan de avlegge grader ved universiteter som Oxford, Harvard og MIT.

Vi har mange studenter som kvalifiserer til et slikt stipend, likevel har det ikke vært mange fra UiB som søker. Jeg skulle ønske enda flere av våre dyktige studenter tok sjansen og søkte på en så spennende mulighet. Derfor sender jeg nå en vennlig påminnelse om at fristen for å søke stipendet går ut 28. september.

Flere av dere har nok hørt om Aker Scholarship allerede, men det er ikke alltid informasjon om slike ordninger når helt ut til de relevante studentene.

Studenter fra alle fag kan søke stipendet, men ofte kan det være fint med en oppfordring og litt bistand i søknadsprosessen. For eksempel vil dere kunne hjelpe med å se over søknadstekster og gi studentene gode referanser, ettersom det ikke bare er karakterer som gjelder.

Dette er en super mulighet for alle våre dyktige studenter.
Nettsiden med all informasjon om Aker Scholarship finner dere her: www.akerscholarship.no

Public PhD defence – Silje Michelsen Solberg

Silje Michelsen Solberg will defend her PhD thesis on Thursday 20th June 2019

Trial lecture: Friday 27th September 2019 at 10.30.
Topic: Psoriasis and comorbidity, what is the connection?”
Place: Auditorium 1, BB-building, Jonas Lies vei 91

Public defense: Friday 27th September 2019 at 12.30.
Title of dissertation: «Systemic inflammation in psoriasis: Circulating immune cells and cytokines»
Place:  Auditorium 1, BB-building, Jonas Lies vei 91

1st opponent: Professor Charlotta Enerbäck, Linköpings universitet, Sverige
2nd opponent: Professor Lone Skov, Københavns universitet, Danmark
3rd member of the comittee: ProfessorEinar Klæboe Kristoffersen, Universitetet i Bergen

The defense will be led by professor Tor Hervig.

New publications

Here are recent publications with contributions from K2 based on last week’s search on PubMed (and optionally articles that have not been included in previous lists). This time the list includes in total 3 recent publications. The entries appear in the order they were received from NCBI. If you have publications that are not included in this or previous lists, please send the references to Hege F. Berg.

Continue reading

This week’s editorial

With the Helse Vest deadlines just around the corner, I would firstly like to wish anyone who is applying the best of luck with their respective applications. Also, please be aware of the possibility of applying for innovative projects through Helse Vest. Later this month we also have deadlines for SFI applications and with several researchers from K2 involved in these applications, Id like to wish applicants there the best of luck!

As institute leader Pål discussed recently when the Rector of UiB was visiting the medical faculty a number of weeks ago, external funds brought in by K2 researchers accounted for approximately 15% of the total external funding attracted to UiB in 2018. That is an incredible statistic for one institute, and demonstrates what can be achieved when state-of-the-art core facilities of the university and the innovative minds of our researchers combine with the clinical potential of Haukeland University Hospital (HUS). With tougher times ahead for UiB, resultant of dwindling funding from the government, the emphasis on attracting external funding, particularly from NFR and EU, will intensify. Resultantly, we need to continuously evolve our collaboration with HUS so that our research remains relevant, competitive and innovative. This will get us some of the way, but as always the devil is in the details – particularly budget details, as many of you with translational projects will have experienced.  The challenge here will be to have greater flexibility and dynamism in how HUS and UiB interact, and that they can find a symbiotic and synergistic relationship to further nurture and not hinder this uniquely innovative research environment at campus Haukeland. Thus, I would urge our leaders both at the university and hospital to find workable solutions around these challenges for the betterment of the research environment and benefit of the faculty’s purse strings.

Finally, I would like to draw your attention to innovation week OPP (https://www.innovasjonsukenopp.no/om-opp/) that starts next Monday 16thof September. OPP is a celebration of innovators! The aim is to to inspire people to explore the possibilities within innovation through events all over our region, aiming to connect entrepreneurs, collaborators and investors. OPP is thus a great place if you have a good idea you want to discuss, if you want to learn more about specific topics or if you want to learn more about innovation.

Holidays, fall and Christmas 

We hope you all had a nice summer and want to remind you that it is now time to plan the remaining vacation for the fall and Christmas. 

The deadline for registering holiday for 2019 in the HR portal is (as usual) 1 OctoberYou can also transfer some days to the next calendar year by sending an application in the HR portal. The application has to state why you are unable to spend the holiday this year, and how you are planning to spend them in 2020. 

Both the application for transfer and registration of holiday are done in the “Holiday” form in the HR portal. Information about vacation regulations can be found in the employee handbook. 

Information on how to register vacation in the HR portal can be found here. 

Free display of BIFF film Monday 17 September: Human Nature

Also this year, K2 organizes the display of one of the year’s BIFF films. The movie is open and free for all.

This year, the choice fell on “Human Nature” by Adam Bolt. More about the movie here:

https://www.biff.no/filmer/article1404929.ece

Welcome to a BIFF movie experience at work and not least: spread the word 😊  Its open for all employees, students, HUS-employees and friends and family.

Hope to see many of you there.

Best regards Julie

Time and place: Large auditorium, Sentralblokken. Tuesday 17th September, 14.30.

Consent for use of photos

When publishing or sharing photos or video where people are the subject, you must comply with the Personal Data Act. The person using/sharing the photos or video must be able to document that consent has been provided. Consent must be voluntary, unambiguous and informed.

More information here. 

New publications

Here are recent publications with contributions from K2 based on last week’s search on PubMed (and optionally articles that have not been included in previous lists). This time the list includes in total 8 recent publications. The entries appear in the order they were received from NCBI. If you have publications that are not included in this or previous lists, please send the references to Hege F. Berg.

Continue reading

Employee interviews

Autumn is often the time for the annual employee interviews. These are part of targeted management and employee development. Therefore, the annual, systematic and mutually prepared personal conversations between an employee and the immediate superior are.

The employee interviews should be linked to K2’s strategic plans and be a real and results-oriented management tool to achieve set goals. The conversation is also an important arena for clarifying expectations of performance, providing mutual feedback and insight into each other’s work situation and addressing the working environment and conditions at the workplace.

The conversation will also be used to uncover competence needs, change and development. Elements related to life phase can be addressed as a theme. The content of the employee interview should be focused on the relationship between the manager and the employee can do something about.

As a natural part of the performance appraisal and the expectation clarification, the contractual conversation about pay is included as part of the employee interview. It is important to remember, then, that we have established wage bargaining systems.

As head of the department, I am in principle responsible for all employees being offered annual employee interviews and am responsible for including the results of the discussions in the unit’s plans and budget. It is not possible to do this for all of K2’s 350 employees, so the conduct of the talks is delegated in such a way that I have employee interviews with the research group leaders while again being responsible for conducting the conversations with their group members. When it comes to administrative staff, Julie Stavnes is the head of administration.

It is important to communicate what you want to achieve in the employee interview and to facilitate the confidentiality needed for the conversation to have added value for both parties. This can be a gradual process that may take some time. To foreign employees, it is important to pay attention to their need to understand overall strategies and goals for the business, the importance of a good and inclusive work environment and the individual’s opportunities for contribution to the community. Relevant topics may also be their social networks, trust vis a vis the leader and colleagues, experience of belonging and in some cases facilitation and integration also outside the workplace.

Finally, I will remind you of the Faculty Lunch on Wednesday 11 September at 11.30-12.20. The Faculty management by Per Bakke and Marit Bakke will discuss the importance of external funding / BOA for the future of our university.