Author Archives: ene057

Invitation to the 12th basic confocal course at MIC

Dear all!

MIC is happy to announce our 12th confocal course. The course is aimed at those of you who want to learn how to use a confocal microscope and will help you get started in the field of confocal imaging either you use the equipment at MIC or at your local institution. The principles of confocal imaging and the parameters to be aware of to be able to acquire the optimal images are the same regardless of which imaging system you use. Continue reading

New Publications

Based on last week’s search for “Department of Clinical Science AND Bergen”. If you have publications which are not covered by this search, send the reference to elin.opheim@uib.no.

Heart Failure Complicating Acute Myocardial Infarction; Burden and Timing of Occurrence: A Nation-wide Analysis Including 86 771 Patients From the Cardiovascular Disease in Norway (CVDNOR) Project.
Sulo G, Igland J, Vollset SE, Nygård O, Ebbing M, Sulo E, Egeland GM, Tell GS.
J Am Heart Assoc. 2016 Jan 7;5(1).

Etiology of Cellulitis and the Validity of New and Old Methods.
Bruun T, Oppegaard O, Kittang BR, Mylvaganam H, Langeland N, Skrede S.
Clin Infect Dis. 2016 Jan 6.

Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats.
Lysne V, Strand E, Svingen GF, Bjørndal B, Pedersen ER, Midttun Ø, Olsen T, Ueland PM, Berge RK, Nygård O.
Nutrients. 2016 Jan 5;8(1).

Etiology of Cellulitis and Clinical Prediction of Streptococcal Disease: A Prospective Study.
Bruun T, Oppegaard O, Kittang BR, Mylvaganam H, Langeland N, Skrede S.
Open Forum Infect Dis. 2015 Nov 25;3(1):ofv181.

Whole genome sequencing of clinical isolates of Giardia lamblia.
Hanevik K, Bakken R, Brattbakk HR, Saghaug CS, Langeland N.
Clin Microbiol Infect. 2015 Feb;21(2):192.e1-3.

New strategy for K2

Per Bakke

I hope you have had a pleasant rest during Christmas and New Year’s Eve. The previous editorial mentioned that it is time for a new strategy plan for K2. The last two days the chairs of the research groups, the institute council, as well as representatives for various groups at the institute have been assembled to discuss a new strategy for K2. The new plan has to take into account the overall strategy documents of the university and the faculty, and also that of the university hospital.

The goals of the new strategy plan should be specific, measureable, ambitious, realistic and achievable within a given time. We will try to make a one page plan so that it is easy to understand and will be taken into account. When the draft of the plan is ready it will be presented in K2Nytt for comments from you. The final version will be approved by the Institute council.

Per

New Names

DHS

We present Dag Harald Skutlaberg, PhD Student at Department of Clinical Science.
Dag Harald started working on his PhD project in January 2016 under supervision of Steinar Skrede (main supervisor), Harald Wiker (co-supervisor) and Haima Mylvaganam (external supervisor MIA/HUS). If anyone wants to say hello, you will find him on the 5th floor in the lab building.

Singel cell seminarium Jan 12, room 9.1-2 Laboratory building 9th floor

Single cell sequencing is a technique for determination of clonal heterogeneity, not only in cancer but also related to aging of tissue. This semimarium will present one technical solution for determination of genetic alteration in single or few cells.

Welcome to Seminarum!

Best,

Bjørn Tore Gjertsen
M: +47 41566248
F: +47 55972950

Inspera webinars spring 2016

New year, more webinars.
This autumn we arranged day and afternoon webinars for sensors every Tuesday. The good response is very inspiring and we can safely conclude that this is a good model for knowledge sharing and dialogue with those who do not have a direct relation to Inspera.

We are now extending the offer with three new themes.
Still free and open to all.
Every Tuesday 13.00: Task Development / Censorship – Biweekly
Every Thursday 13.00: Examination Planning / Implementation – Biweekly

Click here for updated program and registration (in Norwegian). (Feel free to share it !)

With best regards
Student Affairs

Library Courses Spring 2016

The library offers courses in literature searching and handling of references. The courses are meant for employees and students at the University of Bergen and Haukeland University Hospital.  The courses are free of charge.

The following courses are offered this semester:
– EndNote – beginners course 13 January
– PubMed & EMBASE 20 January
– EndNote – beginners course 27 January Continue reading

New Publications

Based on last 3 weeks’ search for “Department of Clinical Science AND Bergen”. If you have publications which are not covered by this search, send the reference to elin.opheim@uib.no.

A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia.
-Hughes T, Hansson L, Sønderby IE, Athanasiu L, Zuber V, Tesli M, Song J, Hultman CM, Bergen SE, Landén M, Melle I, Andreassen OA, Djurovic S.
Biol Psychiatry. 2015 Nov 11.

Promoter SNPs rs116896264 and rs73933062 form a distinct haplotype and are associated with galectin-4 overexpression in colorectal cancer.
Helwa R, Ramadan M, Abdel-Wahab AA, Knappskog S, Bauer AS.
Mutagenesis. 2015 Dec 16.

Low protein A20 in minor salivary glands is associated with lymphoma development in primary Sjögren’s syndrome.
Johnsen SJ, Gudlaugsson E, Skaland I, Janssen EA, Jonsson MV, Helgeland L, Berget E, Jonsson R, Omdal R.
Scand J Immunol. 2015 Dec 18.

CXCR4, CXCL12 and the relative CXCL12-CXCR4 expression as prognostic factors in colon cancer.
Stanisavljević L, Aßmus J, Storli KE, Leh SM, Dahl O, Myklebust MP.
Tumour Biol. 2015 Dec 17.

Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs.
Nepal C, Coolen M, Hadzhiev Y, Cussigh D, Mydel P, Steen VM, Carninci P, Andersen JB, Bally-Cuif L, Müller F, Lenhard B.
Nucleic Acids Res. 2015 Dec 15.

Mortality related to hospital-associated infections in a tertiary hospital; repeated cross-sectional studies between 2004-2011.
Koch AM, Nilsen RM, Eriksen HM, Cox RJ, Harthug S.
Antimicrob Resist Infect Control. 2015 Dec 29;4:57.

Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults – a pilot study.
Berge RK, Ramsvik MS, Bohov P, Svardal A, Nordrehaug JE, Rostrup E, Bruheim I, Bjørndal B.
Lipids Health Dis. 2015 Dec 15;14(1):163.

Borderline Values of Troponin-T and High Sensitivity C-Reactive Protein Did Not Predict 2-Year Mortality in TnT Positive Chest-Pain Patients, Whereas Brain Natriuretic Peptide Did.
Nilsen DW, Mjelva ØR, Leon de la Fuente RA, Naesgaard P, Pönitz V, Brügger-Andersen T, Grundt H, Staines H, Nilsen ST.
Front Cardiovasc Med. 2015 Apr 8;2:16.

Prediction of adverse neonatal outcomes using size centiles and conditional growth centiles.
Karlsen HO, Johnsen SL, Rasmussen S, Kiserud T.
Ultrasound Obstet Gynecol. 2015 Dec 10.

Controlled release metoprolol for aortic regurgitation: a randomised clinical trial.
Broch K, Urheim S, Lønnebakken MT, Stueflotten W, Massey R, Fosså K, Hopp E, Aakhus S, Gullestad L.
Heart. 2015 Dec 9.

Biomarkers and echocardiographic predictors of myocardial dysfunction in patients with hypertension.
Bielecka-Dabrowa A, Michalska-Kasiczak M, Gluba A, Ahmed A, Gerdts E, von Haehling S, Rysz J, Banach M.
Sci Rep. 2015 Mar 9;5:8916.

Interactions of the natural product (+)-avrainvillamide with nucleophosmin and exportin-1 Mediate the cellular localization of nucleophosmin and its AML-associated mutants.
Mukherjee H, Chan KP, Andresen V, Hanley ML, Gjertsen BT, Myers AG.
ACS Chem Biol. 2015 Mar 20;10(3):855-63.

Systemic Analysis of Regulated Functional Networks.
Hernández Sánchez LF, Aasebø E, Selheim F, Berven FS, Ræder H, Barsnes H, Vaudel M.
Methods Mol Biol. 2016;1394:287-310.

Interpretation of Quantitative Shotgun Proteomic Data.
Aasebø E, Berven FS, Selheim F, Barsnes H, Vaudel M.
Methods Mol Biol. 2016;1394:261-73.

Defective PITRM1 mitochondrial peptidase is associated with Aβ amyloidotic neurodegeneration.
Brunetti D, Torsvik J, Dallabona C, Teixeira P, Sztromwasser P, Fernandez-Vizarra E, Cerutti R, Reyes A, Preziuso C, D’Amati G, Baruffini E, Goffrini P, Viscomi C, Ferrero I, Boman H, Telstad W, Johansson S, Glaser E, Knappskog PM, Zeviani M, Bindoff LA.
EMBO Mol Med. 2015 Dec 23.

Approaching a diagnostic point-of-care test for pediatric tuberculosis through evaluation of immune biomarkers across the clinical disease spectrum.
Jenum S, Dhanasekaran S, Lodha R, Mukherjee A, Kumar Saini D, Singh S, Singh V, Medigeshi G, Haks MC, Ottenhoff TH, Doherty TM, Kabra SK, Ritz C, Grewal HM.
Sci Rep. 2016 Jan 4;6:18520.

Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris.
Ding Y, Svingen GF, Pedersen ER, Gregory JF, Ueland PM, Tell GS, Nygård OK.
J Am Heart Assoc. 2015 Dec 31;5(1).

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased 47,XXX in Systemic Lupus Erythematosus and Sjögren’s Syndrome.
Liu K, Kurien BT, Zimmerman SL, Kaufman KM, Taft DH, Kottyan LC, Lazaro S, Weaver CA, Ice JA, Adler AJ, Chodosh J, Radfar L, Rasmussen A, Stone DU, Lewis DM, Li S, Koelsch KA, Igoe A, Talsania M, Kumar J, Maier-Moore JS, Harris VM, Gopalakrishnan R, Jonsson R, Lessard JA, Lu X, Gottenberg JE, Anaya JM, Cunninghame-Graham DS, Huang AJ, Brennan MT, Hughes P, Illei GG, Miceli-Richard C, Keystone EC, Bykerk VP, Hirschfield G, Xie G, Ng WF, Nordmark G, Eriksson P, Omdal R, Rhodus NL, Rischmueller M, Rohrer M, Segal BM, Vyse TJ, Wahren-Herlenius M, Witte T, Pons-Estel B, Alarcon-Riquelme ME, Guthridge JM, James JA, Lessard CJ, Kelly JA, Thompson SD, Gaffney PM, Montgomery CG, Edberg JC, Kimberly RP, Alarcón GS, Langefeld CL, Gilkeson GS, Kamen DL, Tsao BP, McCune WJ, Salmon JE, Merrill JT, Weisman MH, Wallace DJ, Utset TO, Bottinger EP, Amos CI, Siminovitch KA, Mariette X, Sivils KL, Harley JB, Scofield RH.
Arthritis Rheumatol. 2015 Dec 29.

2015 – Looking back at the K2 activities

Per BakkeIn this last editorial of the year it is time to look back at the K2 activities in 2015. With regards to education the main focus has been on the new curriculum in medicine. Although much work remains, the planning is well underway. Digital tools in teaching and examinations are coming. Although the vision of new, fully funded study places in pharmacy has not yet been realized, the Center for Pharmacy has made a great effort of raising the parliamentarians’ awareness of this issue. A new course in galenic pharmacy has been started.

The research activity and the outcome of grant applications have been very good. K2 researchers obtained seven new NFR projects this year, including a part in an infrastructure application that is coordinated from Oslo. K2 received about 60% of the new multi-year grants from Samarbeidsorganet as well as four new EU projects. The total funding received in various applications by K2 employees, will amount to approximately 93 million NOK which is 7 million more than we received from the government. There is however still a large potential for improved external funding.

The technical staff at the department makes important contributions to the successful research. I wish to give credit to Ersilia Bifulco, Jenny Zhang and Tove Folkestad who have reestablished the Forum for Technicians.

HSE is important to all of us. All the staff at K2 has received, or will be offered appraisal interviews annually.

A very tight department economy has left its mark on the activities this year. Although several research groups have received large grants, there are also groups that have not obtained external funding, and the department has had little to offer. I am grateful that people have shown understanding for the limitations linked to the tight budgets. On the bright side, the debt K2 gained by the reorganization of the faculty is now nearly liquidated. This means that in the coming years, there will be some money to promote the K2 activities.

Keywords for next year are the new curriculum in medicine, Ferdighetssenteret, The research unit for health surveys, a new strategy for K2, a structured process for grant applications, and the Forum for Technicians.

Finally, I would like to thank you all for a great effort in 2015, and I wish you all a Merry Christmas!

Per

K2 Administration Christmas Holidays

Jul

From week 52 until Monday 4 January most of the K2 administration is out of office due to Christmas Holidays. The reception will be unmanned from Christmas Eve and until Monday 4 January.

For emergencies or urgent matters that can not wait until 4 January, the Chief of Administration will be available on private mobile phone. We wish  you all a joyful and peaceful Season and happy holidays.

Forum for Technicians has started up again

TFForum for Technicians has started up again, with a committee consisting of Jenny, Ersilia and Tove. In the last forum, that was held in December, one could propose topics for future Forum for Technicians meetings.Gingerbread, tangerines and mulled wine was served. The next meeting in the forum is planned for February 2016. Thanks to the committee for planning and organizing! The picture shows Tove, Beryl and Aud.

2016 Peder Sather Grant Call for Proposals

The Peder Sather Center for Advanced Study supports projects carried out by researchers at UC Berkeley in collaboration with researchers from eight Norwegian universities. The Center offers grants of between $10K and $25K. Funds are made available for one academic year.  Grants can support activities such as workshops, mini-conferences, virtual intellectual exchanges, the undertaking of exploratory and pilot studies, activities such as PhD student exchanges, longer-term stays for Principal Investigators, the collection and analysis of data, and other core research activities.

More information and application form can be found here.
Letter with call for proposals in Norwegian here.
Application deadline: 1 March 2016

Novo Nordisk Foundations Excellence for Young Researchers within Endocrinology

Attached please find an announcement regarding The Novo Nordisk Foundations Excellence Project for Young Researchers within Endocrinology.

Please do not hesitate to contact me, if you have any questions.

Kind regards,
Susanne E. Hede, Ph.D
Scientific Officer
Novo Nordisk Fonden
+45 3527 6629 (direct)
+45 306 74829 (mobile)
suhq@novo.dk
CVR no 10 58 29 89