Author Archives: ene057

New Publications

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Based on last week’s search for “Department of Clinical Science AND Bergen”. If you have publications which are not covered by this search, send the reference to elin.opheim@uib.no.

Single-cell proteomics: potential implications for cancer diagnostics.
Gjertsen BT, Gavasso S, Gullaksen SE, Skavland J.
Expert Rev Mol Diagn. 2016 Feb 19.

Carbamylated LL-37 as a modulator of the immune response.
Koro C, Hellvard A, Delaleu N, Binder V, Scavenius C, Bergum B, Główczyk I, Roberts HM, Chapple IL, Grant MM, Rapala-Kozik M, Klaga K, Enghild JJ, Potempa J, Mydel P.
Innate Immun. 2016 Feb 15.

Why did the authors perform a meta-analysis of studies with primary endpoints they consider clinically unimportant?
Kessler J, Yli BM, Stray-Pedersen B, Jacobsen AF, Saugstad OD, Henriksen T.
Acta Obstet Gynecol Scand. 2016 Feb 16.

TLR-7 and -9 Stimulation of Peripheral Blood B Cells Indicate Altered TLR Signalling in Primary Sjögren’s Syndrome Patients by Increased Secretion of Cytokines.
Karlsen M, Jonsson R, Brun JG, Appel S, Hansen T.
Scand J Immunol. 2015 Dec;82(6):523-31.

Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria.
Berg A, Otterdal K, Patel S, Gonca M, David C, Dalen I, Nymo S, Nilsson M, Nordling S, Magnusson PU, Ueland T, Prato M, Giribaldi G, Mollnes TE, Aukrust P, Langeland N, Nilsson PH.
J Infect Dis. 2015 Dec 1;212(11):1835-40.

Vitamin D status was not associated with ‘one-year’ progression of coronary artery disease, assessed by coronary angiography in statin-treated patients.
Degerud E, Løland KH, Nygård O, Midttun Ø, Ueland PM, Seifert R, Strand E, Bleie Ø, Dierkes J.
Eur J Prev Cardiol. 2015 May;22(5):594-602.

Noli turbare circolos meos!

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Helge-Do not disturb my circles ! (Arkimedes, Syrakus, 212 BC) These famous last words of Arkhimedes were used as he sat in the sand in front his house in Syracuse in Sicily trying to solve his scientific questions when one of the soldiers of the Roman enemy approached him. (Syracuse war part of Magna Graecia). The soldier disliked his answer and killed him with the sword.

It is probably unwise to protect one’s circles in other situations also, as territorial thinking is often an obstacle inside an organization. An important task for the K2 department is to monitor the use of resources, including the use of lab space and equipment, so that we have efficient use of these. In terms of lab space, we have established floor contacts with whom we can now interact directly to optimize the use of lab areas. In addition, K2 will update the list of the more expensive equipment that each group possesses so that we can share this information on the website. Hence we hope it may be easier to know whom to contact if you want to collaborate with someone who has the required equipment. These are sensible use of resources, an opportunity to increase interactions internally at the department, and an opportunity for more “eureka’ moments.

Helge Ræder

NRC: Application Process Spring 2016

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This Spring’s most beautiful adventure is about to start

It’s time to sharpen your pen and write applications to the NRC and other associations which distribute grants. Department of Clinical Science will as earlier focus on collectively preparing good applications to the NRC.

All project applications that emanate from the department must have an approved budget and the signature of the Head of Deparment. Our economists are under pressure in general , and even more so in May, with many applications. Be early if you want your application to be sent. Below you will find the schedule for this year’s application work.

Good luck
Eystein Husebye
Deputy Head
Continue reading →

Invitation to seminar and demonstration with Meso Scale Discovery

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MSDMSD will present and demonstrate their multiplex immunoassay instrument at the Department of Clinical Science (K2), and all research groups are hereby invited to participate. This technology could be of interest to all who analyze biomarkers with platforms such as ELISA and Luminex.

The seminar will be held Wednesday March 2nd at 13:00-14:00, in Auditorium B301 on the 3rd Floor of the Main Hospital Building.
The demonstration of the instrument will take place on the 5th Floor of the lab building, Tuesday March 15th. Continue reading →

Contributions to Debate in Studvest

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We are very interested in getting more professors and researchers to write articles and reader’s letters in Studvest. Many of you are already active in this kind of writing in both BA and BT, but I think it may be advantageous to use Studvest too, as a direct portal to students. With over 13,000 weekly readers you can reach many students through our channels.

Debate Guidelines Studvest:
Reader’s letter – 2500 characters
Article – 4500 characters
Send contributions to debatt@studvest.no
 Continue reading →

Norwegian Flow Cytometry meeting at Solstrand

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Norsk FlowCytometriForening LogoThe Norwegian Flow Cytometry Association organizes its VIII national meeting and a flow cytometry course in Bergen, 18-20 May 2016!
See attached invitation.
The course in flow cytometry (ExCyte: http://expertcytometry.com/) will be held prior to the meeting (18 and 19 May).
The meeting will be held at Solstrand Hotel & Bad 19-20 May 2016.

For information and registration for the course and the meeting click here.

Bergen Summer Research School 2016

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Water, Climate and Society is the overarching theme for next summer’s Bergen Summer Research School, with Professor Terje Tvedt as scientific leader.

From June 13-24, 2016, some of the top international experts on water will gather in Bergen to create a multidisciplinary venue for exploring water as a global challenge.

Seven parallel three-day courses will span disciplines within within natural sciences, health disciplines, social sciences and the humanities: Continue reading →

FORNY2020 – Proof-of-Concept funding – Deadline 1 March

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BTOBergen Technology Transfer (BTO) would like to inform you that you now have the opportunity to apply for FORNY Proof-of-Concept funding.
We ask researchers with relevant projects to contact BTO as soon as possible and before 1 March for initial project discussions. In other words, time is scarce.
More info here.

Sincerely
Kjetil Myhren-Berge
Communications Manager
Bergen Technology Transfer (BTO)
Phone: +47 452 06 896
www.bergento.no

New Publications

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Based on last week’s search for “Department of Clinical Science AND Bergen”. If you have publications which are not covered by this search, send the reference to elin.opheim@uib.no.

The molecular structure of thio-ether fatty acids influences PPAR-dependent regulation of lipid metabolism.
Lund J, Stensrud C, Rajender, Bohov P, Thoresen GH, Berge RK, Wright M, Kamal A, Rustan AC, Miller AD, Skorve J.
Bioorg Med Chem. 2016 Jan 23.

The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M.
Atherosclerosis. 2016 Feb 5;247:64-69.

The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer.
Gansmo LB, Bjørnslett M, Halle MK, Salvesen HB, Dørum A, Birkeland E, Hveem K, Romundstad P, Vatten L, Lønning PE, Knappskog S.
Tumour Biol. 2016 Feb 11.

Novel SLC19A3 Promoter Deletion and Allelic Silencing in Biotin-Thiamine-Responsive Basal Ganglia Encephalopathy.
Flønes I, Sztromwasser P, Haugarvoll K, Dölle C, Lykouri M, Schwarzlmüller T, Jonassen I, Miletic H, Johansson S, Knappskog PM, Bindoff LA, Tzoulis C.
PLoS One. 2016 Feb 10;11(2):e0149055.

BMI and BMI SDS in childhood: annual increments and conditional change.
Brannsether B, Eide GE, Roelants M, Bjerknes R, Júlíusson PB.
Ann Hum Biol. 2016 Feb 10:1-17.

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns.
Joubert BR, den Dekker HT, Felix JF, Bohlin J, Ligthart S, Beckett E, Tiemeier H, van Meurs JB, Uitterlinden AG, Hofman A, Håberg SE, Reese SE, Peters MJ, Kulle Andreassen B, Steegers EA, Nilsen RM, Vollset SE, Midttun Ø, Ueland PM, Franco OH, Dehghan A, de Jongste JC, Wu MC, Wang T, Peddada SD, Jaddoe VW, Nystad W, Duijts L, London SJ.
Nat Commun. 2016 Feb 10;7:10577.

Want some funding?

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Eystein 2Well, then you must at least apply!

The intention of small assets (SMÅFORSK) is to support groups that do not have major funding, to enable them to start new projects. SMÅFORSK is a joint funding from the NRC and the University of Bergen and it has to be used the year it is granted. Applicants can ask for covering of costs of travels, workshops, courses, material, technical and administrative assistance and other operating expenses. In line with the intentions, it is a requirement that the applicant is a permanent employee and an active researcher at the Department of Clinical Science. The Department management will emphasize that the applicants have applied for funding from other sources over the last two years.

Criteria and requirements

  • The research group by its leader is the applicant and the purpose must be discussed and prioritized within the research group
  • It must be documented that the group applied for other external research funding in 2015
  • The funding is for one year and have to be used within the fiscal year, as the funds are not transferable to the next year.
  • The funds will be granted to research groups that do not already have large assets
  • Documentation on how the funds will be spent must be presented

Don’t do like he in the parable of the talents that buried it. Use SMÅFORSK to invest in larger future grants.

Good luck!

The Research Committee at the Department of Clinical Science allocates funds at the next meeting. Send applicaton forms to Siv Johnsen Eggereide siv.eggereide@uib.no
Deadline: 1st March 2016

Applicationform

Eystein Husebye
Deputy Manager

Changes in the introductory seminar

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There are some changes in the introductory seminar for new international employees.
Instead of a full-day seminar there will be two half-day seminars.
Part 1 – runs about once a month. The topic is: Practical information and offers for international researchers at the University of Bergen and Obligations and rights as an employee at the University of Bergen.
In this section, Service Center for International Mobility (SIM) hosts the entire program. Continue reading →

New Names

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Jianhua HanWe present Jianhua Han, MSc in Molecular Medicine.
Jianhua started as a staff engineer in Emmet’s group of Translational Molecular Imaging in Cancer in Janurary 2016.
If you would like to say hello, you will find her on the 9th floor (room 9920) in the lab building.

Announcement of PhD and postdoctoral positions, spring 2016

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New PhD and postdoctoral positions at the Faculty of Medicine and Dentistry:
This spring MOF announces the following grant-funded PhD and postdoctoral positions;
16 PhD positions
12 open positions
2 positions earmarked dentistry (community dentistry and maxillofacial radiology)
2 x 50% positions earmarked the double compentencies course in dentistry (oral surgery and endodontics)

3 postdoctoral positions
2 open positions
1 position earmarked the faculty’s core facilities (Core Facility for Metabolomics (CMB), Core Facility for Flow Cytometry, Molecular Imaging Center (MIC), Core Facility for Proteomics (PROBE), Genomics Core Facility (GCF), The Laboratory Animal Facility, Core Facility for Biostatistics and Data Analysis and Research Unit for Medical Examinations).

Announcements will appear in BT, Job Norway and Euraxess Sunday, 14 February. Application deadline 3 March 2016.

Exemption From Printed Chemical Database

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UiB’s exemption from having a printed chemical database has been extended for 2 years.
As before, there are some requirements we must meet: Easy access to the electronic chemical database (PC, mobile, ipad, etc), and for those chemicals that have the assertion of “patient immediately to hospital” or “emergency medical attention required” (section 4 of SDS) the SDS should be available at the lab.

Regards,
Bente-Lise Lillebø

Call for nominations: Johnny Ludvigsson Prize

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The Swedish Child Diabetes Foundation is pleased to announce that nominations are now welcome for candidates for the 2016 Johnny Ludvigsson Prize for excellent research in childhood and adolescent diabetes.

Please note that nominations must be submitted to reach the Swedish Child Diabetes Foundation office by Friday 13 May this year, as 15 May is on a Sunday.

Please see the enclosed pdf-file for further details.

If you have any questions, please contact the Swedish Child Diabetes Foundation office by telephone +46 13 105690, or e-mail kansli@barndiabetesfonden.se

Best regards,
The Swedish Child Diabetes Foundation

New Publications

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Based on last week’s search for “Department of Clinical Science AND Bergen”. If you have publications which are not covered by this search, send the reference to elin.opheim@uib.no.

Structure – Function studies of HNF1A (MODY3) gene mutations in South Indian patients with monogenic diabetes.
Balamurugan K, Bjørkhaug L, Mahajan S, Kanthimathi S, Njølstad PR, Srinivasan N, Mohan V, Radha V.
Clin Genet. 2016 Feb 8.

Genetics of structural connectivity and information processing in the brain.
Giddaluru S, Espeseth T, Salami A, Westlye LT, Lundquist A, Christoforou A, Cichon S, Adolfsson R, Steen VM, Reinvang I, Nilsson LG, Le Hellard S, Nyberg L.
Brain Struct Funct. 2016 Feb 6.

Reply: Esmolol Added in Cardioplegia.
Dahle GO, Salminen PR, Moen CA, Eliassen F, Jonassen AK, Haaverstad R, Matre K, Grong K.
J Cardiothorac Vasc Anesth. 2016 Jan;30(1):e9-e10.

Participation in research bronchoscopy: a literature review.
Martinsen EM, Leiten EO, Bakke PS, Eagan TM, Grønseth R.
Eur Clin Respir J. 2016 Feb 3;3:29511.

Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice.
Berge RK, Bjørndal B, Strand E, Bohov P, Lindquist C, Nordrehaug JE, Svardal A, Skorve J, Nygård O.
Lipids Health Dis. 2016 Feb 5;15(1):24.

Myocardial function after polarizing versus depolarizing cardiac arrest with blood cardioplegia in a porcine model of cardiopulmonary bypass†.
Aass T, Stangeland L, Moen CA, Salminen PR, Dahle GO, Chambers DJ, Markou T, Eliassen F, Urban M, Haaverstad R, Matre K, Grong K.
Eur J Cardiothorac Surg. 2016 Feb 2.

Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.
Landegren N, Sharon D, Freyhult E, Hallgren Å, Eriksson D, Edqvist PH, Bensing S, Wahlberg J, Nelson LM, Gustafsson J, Husebye ES, Anderson MS, Snyder M, Kämpe O.
Sci Rep. 2016 Feb 1;6:20104.

Does endurance exercise cause atrial fibrillation in women?
Myrstad M, Aarønæs M, Graff-Iversen S, Nystad W, Ranhoff AH.
Int J Cardiol. 2015 Apr 1;184:431-2.

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Per Bakke

Helga

Tuesday was Helga’s funeral. The church at Storetveit was full to the brim. Several hundred people attended. The funeral was a beautiful, warm and a dignified farewell to Helga. For me the lasting memory is of her husband Pål and their fantastic sons who all held moving eulogies for Helga.

I have thought a lot about what Pål said in the church: Helga left life, but she did not leave us.

These are strong words. Although Pål might have meant their family by using the word “us”, I think it applies to us all. And that we should all try to follow up her example. Helga was exceptional at seeing those around her and giving them positive feedback. We can all learn from her.

Academia is very competitive, and so it should be. However, while fighting for positions and resources we should not forget that we are all vulnerable human beings. We must all try to take care of each other, including those who seem to always excel. That would be a dignified and fitting way to honour Helga’s legacy.
Per

New Names

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Steffen

We present Steffen Aleksander Slettevoll, MSc in Medical Biology.
Steffen started as a PhD student at the Influenza Centre – Rebecca Cox in February 2016.
If you would like to say hello, you will find him on the 5th floor in the lab building.

Incorrect parking

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As a consequence of frequent incorrect parking we will remind you that the parking places “on the roof” outside the laboratory building are reserved. Cars parked in the wrong place create a lot of frustration and time lost for those affected. Parking places can not be used without prior agreement with the person who has been allocated the space, or with parking responsible Ingvild Lekven Jonsvoll. If this problem continues, fines and tow-aways will be effected.

Regards
Ingvild Lekven Jonsvoll
Apprentice
Department of Clinical Science
University of Bergen
www.uib.no/klin2