Based on last 9 weeks’ search for “Department of Clinical Science AND Bergen”. If you have publications which are not covered by this search, send the reference to elin.opheim@uib.no.

Subclonal diversification of primary breast cancer revealed by multiregion sequencing.
Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G, Van Loo P, Aas T, Alexandrov LB, Larsimont D, Davies H, Li Y, Ju YS, Ramakrishna M, Haugland HK, Lilleng PK, Nik-Zainal S, McLaren S, Butler A, Martin S, Glodzik D, Menzies A, Raine K, Hinton J, Jones D, Mudie LJ, Jiang B, Vincent D, Greene-Colozzi A, Adnet PY, Fatima A, Maetens M, Ignatiadis M, Stratton MR, Sotiriou C, Richardson AL, Lønning PE, Wedge DC, Campbell PJ.
Nat Med. 2015 Jul;21(7):751-9.

The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey).
Helgeland Ø, Hertel JK, Molven A, Ræder H, Platou CG, Midthjell K, Hveem K, Nygård O, Njølstad PR, Johansson S.
Int J Endocrinol. 2015;2015:164652.

A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.
Kalathur M, Toso A, Chen J, Revandkar A, Danzer-Baltzer C, Guccini I, Alajati A, Sarti M, Pinton S, Brambilla L, Di Mitri D, Carbone G, Garcia-Escudero R, Padova A, Magnoni L, Tarditi A, Maccari L, Malusa F, Kalathur RK, A Pinna L, Cozza G, Ruzzene M, Delaleu N, Catapano CV, Frew IJ, Alimonti A.
Nat Commun. 2015 Jun 18;6:7227.

Transglutaminase 4 as a prostate autoantigen in male subfertility.
Landegren N, Sharon D, Shum AK, Khan IS, Fasano KJ, Hallgren Å, Kampf C, Freyhult E, Ardesjö-Lundgren B, Alimohammadi M, Rathsman S, Ludvigsson JF, Lundh D, Motrich R, Rivero V, Fong L, Giwercman A, Gustafsson J, Perheentupa J, Husebye ES, Anderson MS, Snyder M, Kämpe O.
Sci Transl Med. 2015 Jun 17;7(292):292ra101.

Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.
Oftedal BE, Hellesen A, Erichsen MM, Bratland E, Vardi A, Perheentupa J, Kemp EH, Fiskerstrand T, Viken MK, Weetman AP, Fleishman SJ, Banka S, Newman WG, Sewell WA, Sozaeva LS, Zayats T, Haugarvoll K, Orlova EM, Haavik J, Johansson S, Knappskog PM, Løvås K, Wolff AS, Abramson J, Husebye ES.
Immunity. 2015 Jun 16;42(6):1185-96.

Management of periodontal disease in patients using calcium channel blockers – gingival overgrowth, prescribed medications, treatment responses and added treatment costs.
Fardal Ø, Lygre H.
J Clin Periodontol. 2015 Jul;42(7):640-6.

 Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging.
Vorobyeva AG, Stanton M, Godinat A, Lund KB, Karateev GG, Francis KP, Allen E, Gelovani JG, McCormack E, Tangney M, Dubikovskaya EA.
PLoS One. 2015 Jun 25;10(6):e0131037.

 Autoantibody profiling can predict primary Sjögren’s syndrome years before diagnosis and identify those with early onset and severe disease course.
Theander E, Jonsson R, Sjöström B, Brokstad K, Olsson P, Henriksson G.
Arthritis Rheumatol. 2015 Jun 24.

Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children.
Mohn KG, Bredholt G, Brokstad KA, Pathirana RD, Aarstad HJ, Tøndel C, Cox RJ.
J Infect Dis. 2015 May 15;211(10):1541-9

Exploring the human plasma proteome for humoral mediators of remote ischemic preconditioning–a word of caution.
Helgeland E, Breivik LE, Vaudel M, Svendsen ØS, Garberg H, Nordrehaug JE, Berven FS, Jonassen AK.
PLoS One. 2014 Oct 15;9(10):e109279.

Symptomatic and asymptomatic secondary transmission of Cryptosporidium parvum following two related outbreaks in schoolchildren.
Johansen ØH, Hanevik K, Thrana F, Carlson A, Stachurska-Hagen T, Skaare D, Robertson LJ.
Epidemiol Infect. 2015 Jun;143(8):1702-9.

Irritable bowel syndrome and chronic fatigue 6 years after giardia infection: a controlled prospective cohort study.
Hanevik K, Wensaas KA, Rortveit G, Eide GE, Mørch K, Langeland N.
Clin Infect Dis. 2014 Nov 15;59(10):1394-400.

Matrix M H5N1 Vaccine Induces Cross-H5 Clade Humoral Immune Responses in a Randomized Clinical Trial and Provides Protection from Highly Pathogenic Influenza Challenge in Ferrets.
Cox RJ, Major D, Pedersen G, Pathirana RD, Hoschler K, Guilfoyle K, Roseby S, Bredholt G, Assmus J, Breakwell L, Campitelli L, Sjursen H
PLoS One. 2015 Jul 6;10(7):e0131652.

Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study.
Andrianopoulos V, Wouters EF, Pinto-Plata VM, Vanfleteren LE, Bakke PS, Franssen FM, Agusti A, MacNee W, Rennard SI, Tal-Singer R, Vogiatzis I, Vestbo J, Celli BR, Spruit MA.
Respir Med. 2015 Jun 25. pii: S0954-6111(15)30016-0

The clinical relevance of animal models in Sjögren’s syndrome: the interferon signature from mouse to man.
Maria NI, Vogelsang P, Versnel MA.
Arthritis Res Ther. 2015 Jul 3;17:172

Identification of novel monocistronic HTLV-1 mRNAs encoding functional Rex isoforms.
Rende F, Cavallari I, Andresen V, Valeri VW, D’Agostino DM, Franchini G, Ciminale V.
Retrovirology. 2015 Jul 2;12:58

Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Goulas T, Mizgalska D, Garcia-Ferrer I, Kantyka T, Guevara T, Szmigielski B, Sroka A, Millán C, Usón I, Veillard F, Potempa B, Mydel P, Solà M, Potempa J, Gomis-Rüth FX.
Sci Rep. 2015 Jul 1;5:11969.

Loss-of-function variants in ABCA7 confer risk of Alzheimer’s disease.
Steinberg S, Stefansson H, Jonsson T, Johannsdottir H, Ingason A, Helgason H, Sulem P, Magnusson OT, Gudjonsson SA, Unnsteinsdottir U, Kong A, Helisalmi S, Soininen H, Lah JJ; DemGene, Aarsland D, Fladby T, Ulstein ID, Djurovic S, Sando SB, White LR, Knudsen GP, Westlye LT, Selbæk G, Giegling I, Hampel H, Hiltunen M, Levey AI, Andreassen OA, Rujescu D, Jonsson PV, Bjornsson S, Snaedal J, Stefansson K.
Nat Genet. 2015 May;47(5):445-7.

Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon.
Gansmo LB, Knappskog S, Romundstad P, Hveem K, Vatten L, Lønning PE.
Int J Cancer. 2015 Jul 1;137(1):96-103

One course of adjuvant BEP in clinical stage I nonseminoma mature and expanded results from the SWENOTECA group.
Tandstad T, Ståhl O, Håkansson U, Dahl O, Haugnes HS, Klepp OH, Langberg CW, Laurell A, Oldenburg J, Solberg A, Söderström K, Cavallin-Ståhl E, Stierner U, Wahlquist R, Wall N, Cohn-Cedermark G; SWENOTECA.
Ann Oncol. 2014 Nov;25(11):2167-72.

Screening for latent tuberculosis in Norwegian health care workers: high frequency of discordant tuberculin skin test positive and interferon-gamma release assay negative results.
Gran G, Aßmus J, Dyrhol-Riise AM.
BMC Public Health. 2013 Apr 17;13:353

 A Phospholipid-Protein Complex from Krill with Antioxidative and Immunomodulating Properties Reduced Plasma Triacylglycerol and Hepatic Lipogenesis in Rats.
Ramsvik MS, Bjørndal B, Bruheim I, Bohov P, Berge RK.
Mar Drugs. 2015 Jul 16;13(7):4375-97.

Large-scale genomics unveil polygenic architecture of human cortical surface area.
Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ; Pediatric Imaging, Neurocognition and Genetics Study; Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Hellard SL, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Schork N, Dale AM; Pediatric Imaging Neurocognition and Genetics Study; Alzheimer’s Disease Neuroimaging Initiative.
Nat Commun. 2015 Jul 20;6:7549.

QRS abnormalities of the fetal electrocardiogram, and their implications for ST-interval analysis during labor.
Sletten J, Kessler J.
Acta Obstet Gynecol Scand. 2015 Jul 14

Respiratory Health in Cleaners in Northern Europe: Is Susceptibility Established in Early Life?
Svanes Ø, Skorge TD, Johannessen A, Bertelsen RJ, Bråtveit M, Forsberg B, Gislason T, Holm M, Janson C, Jögi R, Macsali F, Norbäck D, Omenaas ER, Real FG, Schlünssen V, Sigsgaard T, Wieslander G, Zock JP, Aasen T, Dratva J, Svanes C.
PLoS One. 2015 Jul 13;10(7):e0131959.

Matrix M(TM) adjuvanted virosomal H5N1 vaccine induces balanced Th1/Th2 CD4(+) T cell responses in man.
Pedersen GK, Sjursen H, Nøstbakken JK, Jul-Larsen Å, Hoschler K, Cox RJ.
Hum Vaccin Immunother. 2014;10(8):2408-16.

Periconceptional Folic Acid Supplementation and Infant Risk of Congenital Heart Defects in Norway 1999-2009.
Leirgul E, Gildestad T, Nilsen RM, Fomina T, Brodwall K, Greve G, Vollset SE, Holmstrøm H, Tell GS, Øyen N.
Paediatr Perinat Epidemiol. 2015 Sep;29(5):391-400

Pneumothorax size measurements on digital chest radiographs: Intra- and inter- rater reliability.
Thelle A, Gjerdevik M, Grydeland T, Skorge TD, Wentzel-Larsen T, Bakke PS.
Eur J Radiol. 2015 Jul 9. pii: S0720-048X(15)30042-5

CTLA-4 as a genetic determinant in autoimmune Addison’s disease.
Wolff AS, Mitchell AL, Cordell HJ, Short A, Skinningsrud B, Ollier W, Badenhoop K, Meyer G, Falorni A, Kampe O, Undlien D, Pearce SH, Husebye ES.
Genes Immun. 2015 Jul 23

Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Rios-Avila L, Coats B, Ralat M, Chi YY, Midttun Ø, Ueland PM, Stacpoole PW, Gregory JF 3rd.
Am J Clin Nutr. 2015 Jul 22.

Ethnic differences in fetal size and growth in a multi-ethnic population.
Sletner L, Rasmussen S, Jenum AK, Nakstad B, Jensen OH, Vangen S.
Early Hum Dev. 2015 Sep;91(9):547-54

Altered levels of fatty acids and inflammatory and metabolic mediators in epicardial adipose tissue in patients with systolic heart failure.
Fosshaug LE, Dahl CP, Risnes I, Bohov P, Berge RK, Nymo S, Geiran O, Yndestad A, Gullestad L, Aukrust P, Vinge LE, Øie E.
J Card Fail. 2015 Jul 28. pii: S1071-9164(15)00630-2.

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer.
Lu Y, Cuellar-Partida G, Painter JN, Nyholt DR; Australian Ovarian Cancer Study; International Endogene Consortium (IEC), Morris AP, Fasching PA, Hein A, Burghaus S, Beckmann MW, Lambrechts D, Van Nieuwenhuysen E, Vergote I, Vanderstichele A, Doherty JA, Rossing MA, Wicklund KG, Chang-Claude J, Eilber U, Rudolph A, Wang-Gohrke S, Goodman MT, Bogdanova N, Dörk T, Dürst M, Hillemanns P, Runnebaum IB, Antonenkova N, Butzow R, Leminen A, Nevanlinna H, Pelttari LM, Edwards RP, Kelley JL, Modugno F, Moysich KB, Ness RB, Cannioto R, Høgdall E, Jensen A, Giles GG, Bruinsma F, Kjaer SK, Hildebrandt MA, Liang D, Lu KH, Wu X, Bisogna M, Dao F, Levine DA, Cramer DW, Terry KL, Tworoger SS, Missmer S, Bjorge L, Salvesen HB, Kopperud RK, Bischof K, Aben KK, Kiemeney LA, Massuger LF, Brooks-Wilson A, Olson SH, McGuire V, Rothstein JH, Sieh W, Whittemore AS, Cook LS, Le ND, Gilks CB, Gronwald J, Jakubowska A, Lubiński J, Gawełko J, Song H, Tyrer JP, Wentzensen N, Brinton L, Trabert B, Lissowska J, Mclaughlin JR, Narod SA, Phelan C, Anton-Culver H, Ziogas A, Eccles D, Gayther SA, Gentry-Maharaj A, Menon U, Ramus SJ, Wu AH, Dansonka-Mieszkowska A, Kupryjanczyk J, Timorek A, Szafron L, Cunningham JM, Fridley BL, Winham SJ, Bandera EV, Poole EM, Morgan TK, Risch HA, Goode EL, Schildkraut JM, Webb PM, Pearce CL, Berchuck A, Pharoah PD, Montgomery GW, Zondervan KT, Chenevix-Trench G, McGregor S.
Hum Mol Genet. 2015 Jul 30.

Lean-seafood intake reduces cardiovascular lipid risk factors in healthy subjects: results from a randomized controlled trial with a crossover design.
Aadland EK, Lavigne C, Graff IE, Eng Ø, Paquette M, Holthe A, Mellgren G, Jacques H, Liaset B.
Am J Clin Nutr. 2015 Jul 29

13th International Symposium on Sjögren’s syndrome.
Jonsson R.
Scand J Immunol. 2015 May;81(5):273.

Induction of Local Secretory IgA and Multifunctional CD4⁺ T-helper Cells Following Intranasal Immunization with a H5N1 Whole Inactivated Influenza Virus Vaccine in BALB/c Mice.
Trondsen M, Aqrawi LA, Zhou F, Pedersen G, Trieu MC, Zhou P, Cox RJ.
Scand J Immunol. 2015 May;81(5):305-17.

Low folate levels are associated with reduced risk of colorectal cancer in a population with low folate status.
Gylling B, Van Guelpen B, Schneede J, Hultdin J, Ueland PM, Hallmans G, Johansson I, Palmqvist R.
Cancer Epidemiol Biomarkers Prev. 2014 Oct;23(10):2136-44.

Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma.
Haldorsen IS, Popa M, Fonnes T, Brekke N, Kopperud R, Visser NC, Rygh CB, Pavlin T, Salvesen HB, McCormack E, Krakstad C.
PLoS One. 2015 Aug 7;10(8):e0135220.

4-Alkylated Silver-N-Heterocyclic Carbene (NHC) Complexes with Cytotoxic Effects in Leukemia Cells.
Sandtorv AH, Leitch C, Bedringaas SL, Gjertsen BT, Bjørsvik HR.
ChemMedChem. 2015 Aug 6.

Global diversity, population stratification, and selection of human copy number variation.
Sudmant PH, Mallick S, Nelson BJ, Hormozdiari F, Krumm N, Huddleston J, Coe BP, Baker C, Nordenfelt S, Bamshad M, Jorde LB, Posukh OL, Sahakyan H, Watkins WS, Yepiskoposyan L, Abdullah MS, Bravi CM, Capelli C, Hervig T, Wee JT, Tyler-Smith C, van Driem G, Romero IG, Jha AR, Karachanak-Yankova S, Toncheva D, Comas D, Henn B, Kivisild T, Ruiz-Linares A, Sajantila A, Metspalu E, Parik J, Villems R, Starikovskaya EB, Ayodo G, Beall CM, Di Rienzo A, Hammer M, Khusainova R, Khusnutdinova E, Klitz W, Winkler C, Labuda D, Metspalu M, Tishkoff SA, Dryomov S, Sukernik R, Patterson N, Reich D, Eichler EE.
Science. 2015 Aug 6.

Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer.
Flågeng MH, Knappskog S, Gjerde J, Lønning PE, Mellgren G.
PLoS One. 2015 Aug 6;10(8):e0134351.

Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds.
Suliman S, Parajuli H, Sun Y, Johannessen AC, Finne-Wistrand A, McCormack E, Mustafa K, Costea DE.
Head Neck. 2015 Aug 14.

Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6.
Astor MC, Løvås K, Wolff AB, Nedrebø BG, Bratland E, Steen-Johnsen J, Husebye ES.
Endocr Connect. 2015 Aug 13.

Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice.
Skorve J, Hilvo M, Vihervaara T, Burri L, Bohov P, Tillander V, Bjørndal B, Suoniemi M, Laaksonen R, Ekroos K, Berge RK, Alexson SE.
Lipids Health Dis. 2015 Aug 11;14:88.

DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer.
Njølstad TS, Trovik J, Hveem TS, Kjæreng ML, Kildal W, Pradhan M, Marcickiewicz J, Tingulstad S, Staff AC, Haugland HK, Eraker R, Oddenes K, Rokne JA, Tjugum J, Lode MS; ENITEC Network/MoMaTEC Study Group, Amant F, Werner HM, Salvesen HB, Danielsen HE.
Br J Cancer. 2015 May 12;112(10):1656-64.

Intermediate care in nursing home after hospital admission: a randomized controlled trial with one year follow-up.
Herfjord JK, Heggestad T, Ersland H, Ranhoff AH.
BMC Res Notes. 2014 Dec 9;7:889.