CCBIO welcomes you to the first spring seminar of 2026, which will take place on Thursday, January 29th in auditorium 4 at BBB. The event is open to all, and no registration is required. This time, CCBIO researcher Katrin Kleinmanns will be on stage, presenting the work that earned her the Young Cancer Researcher Award.
Kleinmanns is affiliated with the Bjørge and McCormack groups, and her research focuses on new treatment strategies for high-grade serous ovarian cancer (HGSC) – the most aggressive and widespread form of epithelial ovarian cancer. In her talk, she will show how advanced preclinical models can contribute to a better understanding of the disease and pave the way for more targeted therapies.
Topic for the lecture
Topic for the lecture Translational PDX models as a platform to advance therapy in ovarian cancerKleinmanns will present, among other things:
- Establishment of patient-derived xenograft (PDX) models that preserve tumor heterogeneity and the tumor microenvironment
- Identification of CD24 as a biomarker for non-invasive fluorescence imaging and image-guided surgery
- Development of humanized models to test immunotherapies in HGSC
- Targeting chemoresistant cancer cells through personalized treatment strategies
- Profiling the tumor microenvironment to identify predictive and prognostic biomarkers
Despite advances in surgery and targeted therapy, patients with HGSC still have a poor prognosis, with five-year survival rates around 50 percent and relapse rates as high as 75 percent. Kleinmanns’ work seeks to address this need through new models that better reflect the complexity of the disease.
Practical information
- Time: 29 January 2026, at 14.30–15.30
- Location: Auditorium 4, BB building, Jonas Lies vei 91
- Chair: Professor Line Bjørge
- Registration: Not required. UiB students who need ECTS must register in Studentweb.
About CCBIO's seminar series
CCBIO organizes monthly research seminars with national and international speakers. The seminars have three main purposes:
- Disseminate relevant biomarker research to the local research community, especially to students and younger researchers
- Included as part of the courses BMED380 (master) and CCBIO902 (PhD)
- Create a meeting place for informal academic exchange between researchers, PIs, students and other interested parties
All interested parties are welcome to participate.