{"id":7018,"date":"2015-08-21T11:50:10","date_gmt":"2015-08-21T10:50:10","guid":{"rendered":"http:\/\/k2info.w.uib.no\/?p=7018"},"modified":"2015-08-21T13:22:05","modified_gmt":"2015-08-21T12:22:05","slug":"k2-med-artikkel-i-nejm","status":"publish","type":"post","link":"https:\/\/k2info.w.uib.no\/nb_no\/2015\/08\/21\/k2-med-artikkel-i-nejm\/","title":{"rendered":"[:no]K2 med artikkel i NEJM[:en]K2 paper in NEJM[:]"},"content":{"rendered":"

[:no]\"Simon<\/a>Simon Dankel (bildet), Christine Haugen, Gunnar Mellgren og andre ved K2\/Hormonlaboratoriet har delteke i ein studie som vart publisert i New England Journal of Medicine onsdag kveld.
\nStudien beskriv korleis ein vanleg genetisk fedme-variant i FTO-genomr\u00e5det endrar energiforbruket direkte i feittceller, og kva genar og protein som er involvert i denne nye mekanismen. Med FTO-varianten som eksempel, presenterer studien nye omfattande strategiar for \u00e5 utforske og forst\u00e5 mekanismane rundt regulatoriske genetiske variantar i ikkje-kodande DNA, som gir h\u00e5p om \u00e5 finne ei rekke nye m\u00e5l for persontilpassa behandling av vanlege sjukdomar i ti\u00e5ra som kjem.<\/p>\n

Foto: J\u00f8rgen Barth[:en]Sim\"Simon<\/a>on Dankel (pictured), Christine Haugen, Gunnar Mellgren and others\u00a0at K2\/the Hormon Laboratoy have participated in a study that was published in New England Journal of Medicine Wednesday evening.
\nThe study describes how a common genetic obesity-variant in the FTO-gene region alters the energy metabolism directly in fat cells, and which genes and proteins that are involved in this new mechanism. Using the FTO-variant as an example, the study presents new \u00a0comprehensive strategies to explore and understand the mechanisms of regulatory genetic variants in non-coding DNA, which gives hope of finding a number of new targets for personalized treatment of common \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 diseases in the decades to come.<\/p>\n

Photo: J\u00f8rgen Barth[:]<\/p>\n","protected":false},"excerpt":{"rendered":"

[:no]Simon Dankel (bildet), Christine Haugen, Gunnar Mellgren og andre ved K2\/Hormonlaboratoriet har delteke i ein studie som vart publisert i New England Journal of Medicine onsdag kveld. Studien beskriv korleis ein vanleg genetisk fedme-variant i FTO-genomr\u00e5det endrar energiforbruket direkte i…<\/p>\n

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