{"id":5066,"date":"2014-11-27T08:24:50","date_gmt":"2014-11-27T07:24:50","guid":{"rendered":"http:\/\/k2info.w.uib.no\/?p=5066"},"modified":"2014-11-27T08:24:50","modified_gmt":"2014-11-27T07:24:50","slug":"outstanding-award-til-ph-d-kandidat-ved-k2","status":"publish","type":"post","link":"https:\/\/k2info.w.uib.no\/nb_no\/2014\/11\/27\/outstanding-award-til-ph-d-kandidat-ved-k2\/","title":{"rendered":"Outstanding award til ph.d.-kandidat ved K2Outstanding award to PhD-Candidate at K2"},"content":{"rendered":"

\"utstanding<\/a>Boge Lauvsnes tildelt Sj\u00f6gren’s Syndrome Foundation\u2019s Outstanding Abstract Award. I sitt arbeid – Hippocampal Atrophy Is Associated with Anti-NR2 Antibodies in Patients with Systemic Lupus Erythematosus and Primary Sjogren\u2019s Syndrome <\/em>\u2013 har hun vist at en type av anti-NMDA reseptor antistoffer (anti-NR2 antistoffer) for\u00e5rsaker atrofi av hjernestrukturen hippocampus hos mennesker med de immunologske sykdommene SLE og prim\u00e6rt Sj\u00f6grens syndrom. Dette bekrefter dyreeksperimentelle studier som har vist at anti-NR2 antistoffer f\u00f8rer til neuronal d\u00f8d i hippocampus hos mus.<\/p>\n

B\u00e5de ved SLE og prim\u00e6rt Sj\u00f6grens syndrom er slike antistoffer assosiert med kognitiv svikt, og kan utgj\u00f8re en generell mekanisme for cerebral affeksjon ved immunopatier.<\/p>\n

Maria Boge Lauvsnes arbeider i Klinisk immunologisk forskningsgruppe ved Stavanger universitetssjukehus.\"utstanding<\/a>As part of the annual meeting of American College of Rheumatology (ACR) in Boston, USA, PhD-Candidate\/LIS-doctor Maria Boge Lauvsnes was awarded the Sj\u00f6gren\u2019s Syndrome Foundation\u2019s Outstanding Abstract Award. Through her work – Hippocampal Atrophy Is Associated with Anti-NR2 Antibodies in Patients with Systemic Lupus Erythematosus and Primary Sj\u00f6gren\u2019s Syndrome<\/em> \u2013 she has shown that a type of anti-NMDA receptor antibodies (anti-NR2 antibodies) cause atrophy of the brain structure hippocampus in humans with the immunological diseases SLE and primary Sj\u00f6gren\u2019s syndrome. This has been confirmed in animal models, which have revealed that anti-NR2 antibodies cause neuronal death of hippocampus in mice.<\/p>\n

Such antibodies are associated with cognitive failure in both SLE and primary Sj\u00f6gren\u2019s syndrome, and they may constitute a general mechanism for cerebral affection with immunopathies.<\/p>\n

Maria Boge Lauvsnes works for the Clinical Immunological Research Group at Stavanger University Hospital<\/p>\n","protected":false},"excerpt":{"rendered":"

Boge Lauvsnes tildelt Sj\u00f6gren’s Syndrome Foundation\u2019s Outstanding Abstract Award. I sitt arbeid – Hippocampal Atrophy Is Associated with Anti-NR2 Antibodies in Patients with Systemic Lupus Erythematosus and Primary Sjogren\u2019s Syndrome \u2013 har hun vist at en type av anti-NMDA reseptor…<\/p>\n

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